Plaquenil is also known as a treatment for malaria, a blood-borne parasite spread by mosquitoes in many tropical and sub-tropical environments. The usual dose is between one and two tablets per day (200 to 400 mg per day). When Plaquenil works, most patients start to feel improvement after 8-12 weeks. When patients start Plaquenil, doctors usually have them try it for 3 months before they assess the patient to determine if it is working. Chloroquine resistant p falciparum Can plaquenil cause liver damage Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. In 2002, the American Academy of Ophthalmology AAO established ocular examination guidelines for screening patients on Plaquenil therapy. Testing included a comprehensive eye exam that consisted of an assessment of the posterior segment with careful evaluation of associated macular changes or signs of retinal disease. 4 Baseline fundus. Plaquenil can damage the retina of the eye. This can lead to blindness. This problem is most common when high doses are taken for a long time. If you will be taking Plaquenil for a while, it is recommended to have a thorough eye exam before starting it and every three months while taking it. Plaquenil is considered to be pretty safe, but it can rarely damage the eyes. If it isn’t working at all after this time then it is usually stopped. When taking plaquenil which tests should periodically be taken Lab Test while taking Plaquenil - Treato, New Plaquenil Guidelines Calcium chloroquine fc reviewPlaquenil and valacyclovirHydroxychloroquine sulphate tablets ip 200 mgHydroxychloroquine and sunlight My Take on New Ocular Screening Guidelines for Plaquenil By Sergio Schwartzman, MD 12 October 2016 A recent article published by the American Academy of Ophthalmology AAO presented new recommendations for screening of patients being managed with hydroxychloroquine HCQ. My Take on New Ocular Screening Guidelines for Plaquenil.. Plaquenil Warnings and Precautions. Plaquenil Oral Uses, Side Effects, Interactions.. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. Children should not take hydroxychloroquine for long-term therapy. Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests to check your response to hydroxychloroquine. If you are taking hydroxychloroquine for a long period of time, your doctor will recommend frequent eye exams. Hydroxychloroquine should not be taken with other drugs that could cause heart arrhythmias irregular heart rate or rhythm. Taking hydroxychloroquine with these drugs could cause dangerous.