Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Hydroxychloroquine for babisia Otis pregnancy fact sheets plaquenil Plaquenil and losing eyelashes Hydroxychloroquine sulfate tablets usp 200 mg Apr 10, 2019 Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Here are some of the ways in which Plaquenil is used to control lupus symptoms May prevent lupus flares by as much as 50%. Reduce muscle and joint pain. Reduce lupus related rashes. Protect against pleuritis inflammation of the lining of the lungs. Protect against pericarditis inflammation. Plaquenil needs time to build up in your system. As with any AI, you can a remission or a change in the symptoms you feel from day to day, week to week, etc. I know for me I have what I call "good days" and I have "bad days". Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How does plaquenil work in the body Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis., Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Can you take ibuprofen with plaquenil Last week my doc added plaquenil to the mix. I have a pharmacist friend that says it can take up to a year to work, but once its kicks in it can be really good. I suggest you ask your rhuemie for additional help in the meantime. I have had RA going on 12 years, and originally way back when I ws given plaquenil alone and it did nothing. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. How does Plaquenil work?. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. Antimalarials modulate or change the way the immune system works. The exact mechanism of action for hydroxychloroquine and another antimalarial drug chloroquine in RA is not known, but researchers think these drugs decrease production of a number of different chemicals that are important to the immune response. Re Plaquenil - Can It Work Quickly? I tried to get on Plaquenil years ago, and couldn't tolerate it, but now I'm thinking there might be a lessor dose I should try. I'm new to the area, so don't have a rheumy yet. Plaquenil Hydroxychloroquine belongs to a group of medications known as anti-inflammatories and antimalarials. It is used alone or in combination with other anti-arthritic medications to treat rheumatoid arthritis. It helps to reduce pain, stiffness, and swelling in joints.