It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Can you take plaquenil with metoprolol Plaquenil for fatigue Plaquenil and kidney stones Hydroxychloroquine rash Re Lariam vs Plaquenil. Carol, Side-effects such as emotional disturbances, psychosis, and seizures are. possible with Plaquenil hydroxychloroquine but rare. You were probably listening to a discussion about antimalarials used to. treat malaria not RA or lupus - a much different situation. And View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more. Malarone atovaquone / proguanil Remove Malarone from your drug comparison. Plaquenil hydroxychloroquine Remove Plaquenil from your drug comparison. Prescribed for Malaria Prevention, Malaria. Mefloquine And Other Drugs Known To Lower The Convulsive Threshold PLAQUENIL can lower the convulsive threshold. Co-administration of PLAQUENIL with other antimalarials known to lower the convulsion threshold e.g. mefloquine may increase the risk of convulsions. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Is mefloquine in plaquenil Compare Mefloquine vs Plaquenil -, Malarone vs Plaquenil Comparison - Chemical structure of chloroquinePlaquenil confusion Plaquenil and mefloquine should not be combined, as this increases the risk of dangerous problems such as seizures or irregular heart rhythms arrhythmias. If your healthcare provider recommends switching from Plaquenil to mefloquine, you should wait at least 12 hours after your last dose of Plaquenil before taking mefloquine. Drugs That Can Interfere With Plaquenil. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Plaquenil hydroxychloroquine – New Warnings. Mefloquine does not eliminate parasites in the liver phase of the disease, and people with P. vivax malaria should be treated with a second drug that is effective for the liver phase, such as primaquine. Before Using. Drug information provided by IBM Micromedex In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year.