It is often the first line of attack before other more aggressive therapies are added such as methotrexate or rituximab that have bigger impacts on the immune system. I had almost (but not quite) forgotten what these aches and pains feel like, but they're back…I am re-acquainting myself with those symptoms that it tames: the overall flu-like and feverish feeling -- aka malaise -- and joint pain." (Click here to read more). I had a similar experience when I stopped taking plaquenil. Plaquenil superama Benefit of hydroxychloroquine Hydroxychloroquine intoxication Feb 19, 2020 Maintenance adult dosage When a good response is obtained, the dosage may be reduced by 50 percent and continued at a maintenance level of 200 mg to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine is the immunomodulatory drug most frequently used for primary Sjögren syndrome, 7 usually prescribed for patients with fatigue, arthralgia, and myalgia 8-10 rather than severe systemic manifestations. The latter symptoms are treated with corticosteroids and azathioprine, cyclophosphamide, mycophenolate mofetil, or rituximab. Higher dosages 5mg/kg daily lead to higher risk levels. For a 60kg person ~132 lbs, 5mg/kg means 300mg daily. This site has a useful calculator to find your safe dose. If you are currently taking hydroxychloroquine above a safe level. My joint and muscle pain went up and my energy levels went down. No, but it did alleviate some of the symptoms and improve my quality of life. It was one of those situations where I didn't realize the medication was having such an impact until I stopped it. Plaquenil dosage for sjogrens Methotrexate and its benefit for Sjögren’s patients, Hydroxychloroquine for Sjögren Syndrome Symptoms Plaquenil and c diffChloroquine itchChloroquine drug adverse effects Gingylyn September 5, 2016, am #1 I saw a rheumatologist finally today. She prescribed Plaquenil and drew 12 vials of blood to check my clotting factors and test for lupus, as well as a urine test to check my kidneys she said. My concern is if this med will cause me to gain weight. Plaquenil - General - Sjogren's Syndrome Support. Plaquenil/hydroxychloroquine may have more extraglandular.. Hydroxychloroquine? - Symptoms and Medical Treatments.. WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out. How long had you been taking the Plaquenil? I have been taking the generic, hydroxychloroquine, for 11 years. My weight was higher over 200 lbs. My opthamologist suggested I speak to my rheumie about halving the dosage 400 mg/day. When I spoke to my dr. he agreed right away. A little over two years ago I stopped eating meat. Originally, hydroxychloroquine was used to prevent and treat malaria and was considered very effective. Now it is generally used for rheumatoid arthritis, but it has also been shown to work well for juvenile arthritis, some lupus symptoms, and other types of autoimmune conditions.