It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Does plaquenil cause cancer Plasmodium falciparum samuel martin chloroquine Hydroxychloroquine-treatment was associated with a higher rate of live births 67% group A vs 57% group B; P =.05 and a lower prevalence of antiphospholipid antibodies–related pregnancy morbidity 47% group A vs 63% B; P =.004. Feb 19, 2020 Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Hydroxychloroquine sulphate 747-36-4 Not listed Not listed Not listed Not listed Not listed Mutagenic Effects No information available Reproductive Effects No information available. Developmental Effects No information available. Teratogenicity No information available. STOT - single exposure Respiratory system STOT - repeated exposure None known The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Is hydroxychloroquine teratogenicity Hydroxychloroquine Sulfate Tablets, USP 200 mg Rx only, Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects. How long can you stay on plaquenilAralen costoWhat is hydroxychloroquine 200 mg used forStopping plaquenil before surgeryCrest plaquenil Hydroxychloroquine -- Teratogenic Agent There is evidence to indicate that exposure to Hydroxychloroquine an antimalarial drug during pregnancy may have a teratogenic effect on the fetus. A teratogen is a substance that can cause birth defects. Hydroxychloroquine -- Teratogenic Agent Symptoms, Diagnosis.. SAFETY DATA SHEET - Fisher Scientific. Drug Safety in Pregnant & Nursing Women. Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system. PLAQUENIL® hydroxychloroquine sulfate is a white or practically white, crystalline powder, freely soluble in water; practically insoluble in alcohol, chloroform, and in ether. The chemical name for hydroxychloroquine sulfate is 2-4-7-Chloro-4-quinolylaminopentylethylamino ethanol sulfate 11.