If so, would you share a comment on the experience you have had with methotrexate; & the length of time on the medication, benefits noted, and side effects. It can be brief or as detailed as you desire to describe your experience. I used plaquenil for some time on its own, then added in MTX before changing over to leflunomide. Plaquenil eye exam form Generic plaquenil gg320 The news has been buzzing about Venus Williams dropping out of the US Open because of Sjogren's syndrome. As the media has discussed, Sjogren's is an autoimmune disease that attacks the tear and salivary glands and generally results in widespread dryness in the body. In addition to dry eyes and. Sep 05, 2016 I think the Plaquenil is still helping me, but for whatever reason my Sjogren's is just getting more aggressive lately. If a doctor wants to give you a medicine, then they think it might help you. You should at least give it a try. There is no "cure" for Sjogren's at least not yet and medicine won't magically make all your symptoms go away. Plaquenil or Methotrexate? Support Forums Sjogren's Syndrome. And, Plaquenil takes 2-3 months to build up in your system. So in the event that you are one of the people who is actually able to notice a difference in symptoms, you may not notice them for 2-3 months. I would have stayed on MTX if it worked for me, but it didn’t. I didn’t drop plaquenil until I had been on a biologic for about six months. Plaquenil and methotrexate for sjogren's syndrome Sjogren's syndrome - Diagnosis and treatment - Mayo Clinic, Plaquenil - General - Sjogren's Syndrome Support Chloroquine 250 mg thuocHydroxychloroquine street valuePlaquenil sarcoidosis treatment Methotrexate and Sjogren syndrome - from FDA reports Summary Sjogren syndrome is found among people who take Methotrexate, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have Dizziness. Will you have Sjogren syndrome with Methotrexate - eHealthMe. Plaquenil or Methotrexate? -. Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment. Mar 18, 2012 Plaquenil won't directly affect dry-eye, but it can slow the progress of the disease and, therefore, hopefully slow down the rate at which your body is attacking your tear glands in other words, it might not make things better, but it may keep them from getting worse. Plaquenil has been a lifesaver for me in so many ways. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Jul 19, 2010 Methotrexate is a common medication that is prescribed to patients diagnosed with Sjogren’s syndrome and other autoimmune diseases. Methotrexate replaced the more powerful and toxic antifolate aminopterin starting in the 1950s.