Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Hydroxychloroquine sulfate tabs Why does chloroquine itch Apr 21, 2017 I had to stop methotrexate about 7 months ago for my RA, due to bad side effects after using it successfully for 10 years. As an alternative, my rheumy put me on HCQS, also known as plaquenil, along with. Hello hope everyone is well just a quick question, i have been on methotrexate for 2 months increasing from 7.5 to 15 and now to 25mg.weekly now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. Learn when your doctor might switch you to one of these drugs, and how to make the change. like methotrexate, sulfasalazine, hydroxychloroquine, or leflunomide. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. How to switch from plaquenil to methotrexate RA - what else can I try, now on methotrexate, have tried., Methotrexate and plaquenil - Plaquenil dosing ideal body weightMédicament mylan-hydroxychloroquineBuy plaquenil cheapCan i take plaquenil and prednisone together Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Compare Plaquenil vs Methotrexate -. How You Can Work With Your Doctor to Switch Your RA Meds. Plaquenil Uses, Dosage & Side Effects -. This is a really good article. I am on Plaquenil and Methotrexate. We tried Enbrel for a year, then had to switch to Remicade. Still not working well, we have increased the dosage twice. I am on Prednisone 5mg just as a temporary measure until I go back next week. It is time to move on, but I couldn’t decide between Rituxin, Acterma, or Orencia. No Plaquenil hydroxychloroquine generally takes 6-12 weeks to be effective and can take up to 6 months to reach its maximum benefit. Methotrexate can take 2-3 months and the dose can be increased to as high as 25 mg weekly if lower doses are not adequate.more See 1 more doctor answer Methotrexate is an extremely important therapy for Sjögren’s and many other rheumatic and inflammatory. Follow us on our journey to change the face of Sjogren’s. Methotrexate and its benefit for Sjögren’s patients. Posted on. NSAIDs, low doses of steroids and Plaquenil hydroxychloroquine are often managed with methotrexate.