I have been on plaquenil for about 10 weeks now without much success. I have had the sickness to my stomach and not felt like me including exhausted but it's not as bad as I feared. My hair is coming out slightly Not in clumps are anything, just a little here or there. My doctor said if I don't feel better in a few more weeks, we could switch my medicine. Really though in order not to have worse things happen it is what we have to do. I switched back to cymbalta three days ago and have experienced huge relief. Hydroxychloroquine and phototherapy Bpi nite burn and hydroxychloroquine Hydroxychloroquine dogbone Chloroquine molecular weight Oct 09, 2015 I was on both for 2 years without a problem, I've stopped taking plaquenil but am still on 20mg methotrexate per week for closer to 3 years now without incident. Yes it's scary to begin with but when your quality of life slowly returns it's all worthwhile. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. Doctors generally recommend regular eye exams while on Plaquenil, so that early changes can be caught. Once abnormalities are discovered, toxicity has already occurred. Interaction between Methotrexate and Plaquenil There is no known interaction between Methotrexate and Plaquenil in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. Vitamin B-12 might help with the hair, ask your doctor about that, well wishes to you and I hope the mtx can help you....((((((((((((((((((((((((((((((((((((((((((((((Jeanneac)))))))))))))))))))))))))))))))))))))))))healing hugz and well wishes and keep us posted on how your doing... Had headaches with the plaquenil so went to the sulfar and predisone. (like i did friday) Take care of yourself and big(((HUGS))) on your journey. He said it would be one that they would have to more closely monitor me on with some blood tests. I was thinking it was methotrexate but I do not want my hair to fall out. It might be coincidence but since on the plaquenil, I have noticed a growth spurt of hair especially at the hairline. Plaquenil made me sick, so I can't take it either, but there are other medicine out there,the doctor's will get you on something that'll help, keep hope..wishes to you and try the methotrexate,to see if it can help... I know it is scary but anything to stop the pain and misfunction of not being able to use my hands or move my knees or not have my ankles cave out and fall. I suspected that I had fibromyalgia on top of the inflammation. I am so relieved but hope I don't start having bad side effects from it like I did before with a very dry mouth and gritting my teeth at night. Can you take methotrexate without plaquenil Canada Plaquenil - Canadian Drugs for Rheumatoid Arthritis., Taking Plaquenil for Rheumatoid Arthritis Improvement of ra with hydroxychloroquineArava and plaquenilChloroquine cyanideDoes plaquenil cause kidney damage Periodontal disease is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Methotrexate, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. Will you have Periodontal disease with Plaquenil - eHealthMe. Compare Methotrexate vs Plaquenil for Lupus - Comprehensive.. Methotrexate or Plaquenil - Scleroderma - Inspire. Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. Methotrexate and plaquenil. now been given plaquenil 400mg daily, has anyone else been on this mixture and has it worked or how long should i wait to see if it works. i am still in so much pain everyday and hoping for some relieve soon. Methotrexate Remove Methotrexate from your drug comparison. Plaquenil hydroxychloroquine Remove Plaquenil from your drug comparison. Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers.