Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Is plaquenil safe to take during pregnancy Hydroxychloroquine and doxycycline Plaquenil steven johnson syndrome Hydroxychloroquine in lupus pregnancy This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative. And screening for hydroxychloroquine retinopathy should be given to all patients. GPP All patients should undergo 10-2 Humphrey visual fields testing using a white stimulus, followed by pupillary dilation and imaging with both spectral domain optical coherence tomography SD-OCT and widefield fundus autofluorescence FAF. B Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil retnopathy oct Eye screening for patients taking hydroxychloroquine Plaquenil, Hydroxychloroquine and Chloroquine Retinopathy. What happens if you stop taking your plaquenilPlaquenil alopecia areata alopecia totalisChloroquine is ineffective on the exoeryhtoChloroquine and early pregnancyPlaquenil side effects gas To detect chloroquine toxicity, the American Academy of Ophthalmology recommends performing fundus examinations, 10-2 automated visual fields, and at least one objective test multifocal electroretinography mfERG, fundus autofluorescence imaging, or spectraldomain optical coherence tomography SD-OCT. 1 By contrast, Amsler grid testing. Retina Today - Evaluating Hydroxychloroquine Toxicity With.. Recommendations on Screening for Chloroquine and.. Hydroxychloroquine Plaquenil Toxicity and.. Apr 20, 2011 8. Kellner S, Weinitz S, Kellner U. Spectral domain optical coherence tomography detects early stages of chloroquine retinopathy similar to multifocal electroretinography, fundus autofluorescence and near-infrared autofluorescence. Br J Ophthalmol. 2009 Nov;93111444-7. 9. Lai TY, Ngai JW, Chan WM, Lam DS. Today it is recommended that every single person on Plaquenil get a visual field 10-2 test, plus one of the three other highly sensitive screening tests the FAF fundus autofluorescence imaging, the SD-OCT spectral domain optical coherence, or the multifocal electroretinogram mfERG,” Thomas says. Hydroxychloroquine Retinopathy with SD-OCT Changes and Minimal Fundus Changes. The images shown here refer to the same case as "Hydroxychloroquine Retinopathy with Minimal Fundus Changes". This 68 year old woman with systemic lupus erythematosus had been on hydroxychloroquine at a dosage of 400 mg/d 6.52 mg/kg/d for eight years.