Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Tier for hydroxychloroquine Chloroquine and bacterial resistance Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. They pretty much all restarted the drug and said they would stay on it cause it was working. I would assume from this that people had sudden and quite severe flares when stopping the plaquenil. There is always the chance that some people might interpret this as withdrawal, but I think it is probably always in the eye of the beholder. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? Plus I will be honest the whole eye site thing even though rare has always freaked me out. I went off of it to see if I can manage not being on it as my lupus isnt as severe as other cases but already I am feeling very fatigued and my legs feel heavy if that makes sense. I can discuss alternatives with my DR at my next appt but my DR feels as though the plaq is the best bet for my level of illness. If so are you just dealing with Lupus symptoms or did you take another med? I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. Discontinuing plaquenil Hydroxychloroquine Reviews Everyday Health, Hydroxychloroquine MedlinePlus Drug Information Retinal changes with the use of hydroxychloroquineChloroquine rheumatoid arthritis mechanism Dr. Fung’s case involved a 48-year-old woman with lupus. Nine years after discontinuing medical therapy, the patient had new scotomas, difficulty reading and progression of bull’s-eye maculopathy. Plaquenil’s long half-life in the body can cause irreversible and progressive damage, Dr. Fung said. Rx Side Effects New Plaquenil Guidelines and More - American.. Let me tell you what weaning down from Plaquenil is like.. Stopping Plaquenil? DailyStrength. Here are 10 things to keep in mind when using Plaquenil Take it on a regular schedule, meaning at the same time each day. Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. Plaquenil ® hydroxychloroquine – New Warnings • On January 27, 2017, the FDA approved new updates to the. Warnings. section of the Plaquenil hydroxychloroquine drug label regarding cardiac effects, including cardiomyopathy and QT prolongation, and hypoglycemia. • Plaquenil is indicated for the treatment of uncomplicated malaria due to Aug 26, 2016 So I ran out of my plaquenil and the Rheum. that prescribed it I am no longer seeing and wont re-fill it and I dont see my new Rheum. until Decemeber 23rd. I am nervous to see what will happen. The pharmacist said there wont be any danger just stopping it. Im just nervous to see what my body will do. Has anyone gone off the plaquenil and what happened? I hear my new Rheum. is all for it so I.