Bone mineral density problem #1: Glucocorticoids These wonder drugs work fast to fight inflammation from rheumatoid arthritis, lupus, fibromyalgia, Lyme disease, or a nasty rash from contact dermatitis. But they’re also the most common source of bone loss from medications, according to a 2010 joint study by the University of Colorado in Denver and the College of Pharmacy & Department of Medicine at Dalhousie University in Halifax. Plaquenil prevebt lupus flare Hydroxychloroquine and ibuprofen together Visual field testing for plaquenil toxicity Botox and plaquenil According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. I have osteoporosis and have been on Actonel for 18 months. It has done wonders and reversed all of my bone loss, some greatly and some moderately, but all areas have improved. There are so many contributing factors to it that there is no telling what caused it in either of us. Genetic predisposition did not help in my case. Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria. A Canadian study, published in a 2013 issue of the journal Osteoporosis International, found that prolonged use of glucocorticoids within the last 12 months reduced bone mineral density and increased fracture risk in the participants.“The risk of bone loss continues for as long as women stay on glucocorticoids,” Wei says. Glucocorticoids (with brand names like Prednisone, Flovent, Actonel, Decadron, Aristocort and Depo-Medro) trigger gradual bone loss, by decreasing its formation, reducing calcium absorption in the intestine and increasing urinary excretion of calcium, an important skeletal nutrient. Plaquenil does it cause bone loss Will you have Osteoporosis with Plaquenil - eHealthMe, Plaquenil Hydroxycholorquine - Arthritis - MedHelp Hydroxychloroquine dental side effectsHydroxychloroquine plateletsIs there a difference between plaquenil and generic Summary Bone loss is found among people who take Plaquenil, especially for people who are female, 50-59 old also take medication Zometa, and have Osteoporosis. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. Will you have Bone loss with Plaquenil - eHealthMe. Plaquenil. Rx Side Effects New Plaquenil Guidelines and More.. Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. What is Plaquenil Hydroxychloroquine? Learn about drug imprint, side effects, uses treating, dosage, interaction, overdose, and warnings. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. hair loss. This is not a complete list of side effects and others may occur. PLAQUENIL has been shown to cause severe hypoglycemia including loss of consciousness that could be life threatening in patients treated with and without antidiabetic medications. Patients treated with PLAQUENIL should be warned about the risk of hypoglycemia and the associated clinical signs and symptoms.