The association between HCQ use and pregnancy outcomes (early spontaneous abortion, fetal death, and preterm and term live birth) was analyzed using generalized estimating equations (GEE) accounting for the occurrence of multiple pregnancies per patient. Analyses were adjusted for antiphospholipid antibody (a PL) status. 110 pregnancies (63 mostly Caucasian patients) were included, of which, in 30, HCQ was used; overall occurrence of flares was low (non-HCQ group: 5 mild (6.4%) and 2 severe (2.6%); HCQ group: 2 mild (6.7%) and no severe flares). 10-2 plaquenil Chloroquine phosphate autophagy Sunday, 01 July 2018. In every pregnancy, a woman starts out with a 3-5% chance of having a baby with a birth defect. This is called her background risk. This sheet talks about whether exposure to hydroxychloroquine may increase the risk for birth defects over that background risk. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Pregnant, considering becoming pregnant, or lactating, please discuss this with your doctor before taking this medication. However, hydroxychloroquine has been shown to be safe during pregnancy and breast feeding. Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common Apart from disease flares during pregnancy, SLE patients have an increased risk of intrauterine growth restriction (OR 2.6), (pre)eclampsia (OR 3.0), and preterm birth (OR 2.4) compared to the healthy population . The HCQ group showed a trend towards lower dosage of prednisone (OR 0.2 (95% CI 0.0–1.4); Pregnancy constitutes a challenge in patients with systemic lupus erythematosus (SLE). Is plaquenil safe for pregnancy Lupus and Pregnancy Tips for Living with Lupus While Pregnant, Plaquenil Oral Uses, Side Effects, Interactions. Plaquenil to treat ms PLAQUENIL is indicated for the suppressive treatment and treatment of acute attacks of malaria due to Plasmodium vivax, P. malariae, P. ovale, and susceptible strains of P. falciparum. It is also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis. PLAQUENIL®. PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Hydroxychloroquine Plaquenil. As for your potential pregnancy, as I said in my response to you, I believe Plaquenil is now considered to be safe during pregnancy and breastfeeding. I have a good friend with EDS too and I’ve asked her what pregnancy was like for her. Apr 10, 2019 It is not known whether Plaquenil will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant. Malaria is more likely to cause death in a pregnant woman. If you are pregnant, talk with your doctor about the risks of traveling to areas where malaria is common. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus.