It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Chloroquine retinal cell Chloroquin and ferroquine structure What does plaquenil do to the immune system A cookie-cutter approach to dosing Plaquenil hydroxychloroquine, Sanofi-Aventis, an anti-malarial drug that has been used as a treatment for systemic lupus erythematosus and rheumatoid arthritis. When treating lupus or arthritis, Plaquenil is usually given daily for several weeks or months. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 6 months of treatment. While using Plaquenil, you may need frequent blood tests and vision exams. Rheumatoid Arthritis. The action of hydroxychloroquine is cumulative and may require weeks to months to achieve the maximum therapeutic effect see CLINICAL PHARMACOLOGY. Initial adult dosage 400 mg to 600 mg 310 to 465 mg base daily, administered as a single daily dose or in two divided doses. Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Plaquenil dose for arthritis Plaquenil hydroxychloroquine sulfate dosing, indications., Plaquenil Uses, Dosage & Side Effects - Use of plaquenil for osteoarthritisHow to bill for following plaquenil retinaPlaquenil side effects gasPlaquenil itching side effects Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine Plaquenil Side Effects & Dosage for.. Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Hydroxychloroquine Plaquenil is primarily used in combination with other drugs, including methotrexate and/or sulfasalazine for moderate to severe Rheumatoid Arthritis. It is only prescribed alone in patients with very mild symptoms, who are RF negative and have non-erosive disease. Generally, hydroxychloroquine is given in 200 mg or 400 mg doses, once per day. Higher doses can sometimes be used, but only in adults and not for all cases. Two plaquenil a day and 2400 mg of ibuprofen a day that's 12 regular dose! and I went into total remission. Of course my stomach is crap now. After 25 years of remission, the RA returned.