It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine sulfate drug classification Getting off hydroxychloroquine Aralen and food Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. For treatment of arthritis Adults—At first, 400 to 600 milligrams mg taken as a single dose or in two divided doses once a day. Then, 200 to 400 mg taken as a single dose or in two divided doses once a day. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Plaquenil dosage for osteoarthritis Plaquenil Dosage Guide -, Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis Can hydroxychloroquine cause vision changesTake vitamin d with plaquenilPlaquenil hyponatremia User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Plaquenil User Reviews for Rheumatoid Arthritis at. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Inflammatory Osteoarthritis And Plaquenil. The hydroxychloroquine effectiveness in reducing symptoms of hand osteoarthritis HERO trial was designed to this end. Dosage will be determined as per the schedule in Table 4. Table 4. Rice JR, Allen NB. Treatment of erosive osteoarthritis with hydroxychloroquine. Arthritis Rheum. Background/Purpose Hydroxychloroquine HCQ is a widely-used medication in many rheumatologic conditions. The most worrisome toxicity is irreversible damage to retinal pigment epithelium which can lead to blindness. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity1. According to these Feb 19, 2020 Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days.