They are most common among people with weak immune systems. People with certain health conditions may need to take medications with side effects that can weaken your immune system and put you at risk for fungal infections. Vision test for plaquenil Grapefruit and plaquenil Glaucoma and plaquenil Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Plaquenil is an immunomodulatory drug DMARD that works by suppressing the immune system to prevent it from damaging tissues and joints. The immune system helps protect the body from harmful substances such as infectious agents and bacteria. Plaquenil is generally well-tolerated, but side effects are possible. Common side effects linked to Plaquenil include nausea and diarrhea. Taking the medication with food eases nausea for most people taking the drug. Less common side effects include skin rashes, hair thinning, and weakness. Fungal infections can range from mild to life-threatening. Specifically, corticosteroids and TNF (tumor necrosis factor) inhibitors are two types of medications that can increase your chances of getting a fungal infection. Does plaquenil weaken the immune system Will you have Immune system disorder with Plaquenil - eHealthMe, Plaquenil Chloroquine trade name generic namePlaquenil color pillPlaquenil peripheral neuropathy Aug 02, 2010 Yes, Plaquenil suppresses the immune system. Autoimmune disease such as Sjogrens occurs when the body gets "confused" and attacks healthy tissue instead of just attacking the germs. Basically, the immune system is a bit out of control. Plaquenil works by suppressing the immune system. Do either hydroxychol/Plaquenil put you at risk for greater.. Taking Plaquenil for Rheumatoid Arthritis. The Immunity Challenge How aging affects your immune system. But you can’t even compare it to the only other things I have to treat lupus—prednisone, where 100 percent of people get side effects, or immunosuppressive drugs, which suppress the immune system, potentially causing infections, low blood counts, and liver toxicity. Hydroxychloroquine suppresses the immune system and should not be combined with drugs that also suppress the immune system or live vaccines. QUESTION The term arthritis refers to stiffness in the joints. The production of autoantibodies in people with lupus and other autoimmune diseases causes the immune system to target the body’s own cells for destruction. For example, about 98% of people with lupus possess antinuclear antibodies ANA, which can attack the nucleic material of your cells.