I have been found that I have seriously low platelet levels and was wondering if this drug plaquenil could have something to do with it. My mom used this drug for treating symptoms of rheumatoid arthritis. I say "treated" because I never was placed on any medication and my treatment consisted of regular CBC's to count my platelets, which ranged from 28,000 three years ago to 125,000 in April. Ara hydroxychloroquine Surgical chloroquine prep The drug-induced thrombocytopenia, mechanical destruction of the platelets, and hemodilution are common causes of low platelet count encountered after open heart surgery. 1 Although drug-induced immune thrombocytopenia has a mild clinical course in most cases, in this case it was severe may depend of cross-reaction between acetyl salicylic acid and hydroxychloroquine. Summary. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. According to the New Zealand Dermatological Society, Plaquenil can cause abnormalities in blood counts. An abnormally low number of white blood cells can lead to infection, because white blood cells defend the body against bacteria. Low platelet count thrombocytopenia can lead to easy bleeding and bruising. I was fortunate to have to switch hemotologists in April because my new Hemo did some additional tests which suggested Lupus. I was dx with Lupus in May, after being "treated" for idiopathic thrombocytopenia purpura for three and a half years. Plaquenil low platelets Hydroxychloroquine Plaquenil Side Effects & Dosage for., Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Can plaquenil cause numbness in tailbone area and legsWhat does the drug plaquenil doGoodrx hydroxychloroquinChloroquine endosomal escapePka of chloroquine Plaquenil and Thrombocytopenia - from FDA reports Summary Thrombocytopenia is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years, also take medication Enbrel, and have High blood pressure. Will you have Thrombocytopenia with Plaquenil - eHealthMe. Long-Term Side Effects of Plaquenil for Rheumatoid.. Question Lupus and low platelet count.. Low white cells are a part of the autoimmune issue. This is something that I have dealt with for years. I have been on the Plaquenil a couple of years now and my immunologist told me that Plaquenil doesn't cause the same issues as the DMARDS or the methotrexates, imuran, etc. Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Dugan on plaquenil and low wbc This drug can effect the bone marrow and make the white blood count and platelets low. Your doctor may want to stop this medication, but don't stop it till you talk to the doctor. Good luck! Im also on Plaquenil once a day now instead of 2 cause they can cause platelets to be low as well so they reduced that. Thanks so much and sorry so long Brandi. renalupie1 responded My mother had many many health issues. It may come to that since Ive been having symptoms of the low platelets for about a few months unknowingly, but the.