Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Taking plaquenil and hands still swollen Basic description of chloroquine Plaquenil and dark spots Hydroxychloroquine immunosuppressive Western blot analysis of extracts from HeLa cells, mock transfected or transfected with rat LC3B, and from HT-1080 and A20 cells, untreated or chloroquine-treated 50 μM, overnight, using LC3B Antibody. Chloroquine is commonly used to study the role of endosomal acidification in cellular processes 2, 3, such as the signaling of intracellular TLRs. Moreover, Chloroquine inhibits autophagy as it raises the lysosomal pH, which leads to inhibition of both fusion of autophagosome with lysosome and lysosomal protein degradation 4. References. 1. Chloroquine. In some countries, this medicine may only be approved for veterinary use. In the US, Chloroquine chloroquine systemic is a member of the following drug classes amebicides, antimalarial quinolines and is used to treat Amebiasis, Malaria, Malaria Prevention and Sarcoidosis. US matches Chloroquine; Chloroquine Oral, Intramuscular The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine molecular weight Chloroquine hydrochloride C18H28Cl3N3 - PubChem, Chloroquine for research Cell-culture tested InvivoGen Gray nails and plaquenilPlaquenil patient reviews Molecular mass molecular weight is the mass of one molecule of a substance and is expressed in the unified atomic mass units u. 1 u is equal to 1/12 the mass of one atom of carbon-12 Molar mass molar weight is the mass of one mole of a substance and is expressed in g/mol. Chloroquine diphosphate ≥99%HPLC Selleck ATM/ATR.. Chloroquine -. Chloroquine diphosphate salt - Sigma-Aldrich. Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth. Molecular weight— Chloroquine 319.88 Chloroquine hydrochloride 392.80 Chloroquine phosphate 515.87 Mechanism of action/Effect Antiprotozoal—Malaria Unknown, but may be based on ability of chloroquine to bind to and alter the properties of DNA. Chloroquine also is taken up into the acidic food vacuoles of the parasite in the erythrocyte. Sigma-Aldrich offers a number of Chloroquine phosphate products. View information & documentation regarding Chloroquine phosphate, including CAS, MSDS & more.