Begin 1-2 days before travel, daily during travel, and for 7 days after leaving. Manufacturer Recommendations: 15 mg base (26.3 mg salt) orally once a day for 14 days Comments: -Recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or after the end of chloroquine phosphate suppressive therapy in vivax malaria-endemic area -Should be given with chloroquine phosphate (destroys erythrocytic parasites and stops attack) to destroy exoerythrocytic parasites Use: For the radical cure (prevention of relapse) of malaria due to Plasmodium vivax US CDC Recommendations: 30 mg base (52.6 mg salt) orally once a day for 14 days -Alternate regimen: 45 mg base (78.9 mg salt) orally once a week for 8 weeks Comments: -For the radical cure of malaria due to P vivax or P ovale -Since this drug usually is not active against asexual erythrocytic forms of plasmodia, it should be administered with other appropriate antimalarial agents. Chloroquine kinase Eye problems on hydroxychloroquine Plaquenil and veins Infections should receive chloroquine prophylaxis 300 mg base po once a week during pregnancy. After delivery, patients with normal G6PD activity should be treated with primaquine or tafenoquine or continue with chloroquine prophylaxis for a total of 1 year. Primaquine can be used during breastfeeding if the infant is found When chloroquine, doxycycline, or mefloquine is used for primary prophylaxis, this drug should be used during the last 2 weeks of postexposure prophylaxis.-When atovaquone-proguanil is used for prophylaxis, this drug may be used during the last week of atovaquone-proguanil plus an additional 7 days. Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include IBM Watson Micromedex updated, Cerner Multum™ updated, Wolters Kluwer™ updated. -The alternate regimen is recommended for patients with borderline glucose-6-phosphate dehydrogenase (G6PD) deficiency or as an alternative to the daily regimen. -This drug eradicates any hypnozoites that may be dormant in the liver and, thus, prevent relapses. Chloroquine po 300 mg daily prophylaxis The risk of antimalarials in patients with renal failure, Primaquine Dosage Guide with Precautions - Taking plaquenil and metoprolol togetherHydroxychloroquine bleeding and surgeryWhat are chloroquine phosphate tablets used forPlaquenil alternatives lupus Initially by mouth using tablets. For Child 14–17 years body-weight 45 kg and above. 310 mg once weekly, alternatively by mouth using syrup 300 mg once weekly, started 1 week before entering endemic area and continued for 4 weeks after leaving. CHLOROQUINE Drug BNF content published by NICE. Hydroxychloroquine Professional Patient Advice -. CHLOROQUINE PHOSPHATE TABLETS, USP 250 MG and 500 MG. Chloroquine is used for the prophylaxis of malaria in areas of the world where the risk of chloroquine-resistant falciparum malaria is still low. It is also used with proguanil when chloroquine-resistant falciparum malaria is present. However, this combination may not be ideal. Chloroquine per week starting at least 1 week before. traveling to the area where malaria transmission occurs. They should take one dose per week while there, and for 4 consecutive weeks after leaving. The weekly dosage for adults is 300mg base 500mg salt. Syrup contains 50 mg/5 mL of chloroquine base equivalent to 80 mg/5 mL of chloroquine phosphate. Unlicensed use Chloroquine doses for the treatment and prophylaxis of malaria in BNF publications may differ from those in product literature.