Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil dosages If i go off plaquenil can i go back on Each tablet contains 500 mg of Chloroquine phosphate USP, equivalent to 300 mg Chloroquine base. Inactive Ingredients colloidal silicon dioxide, dibasic calcium phosphate, hydroxypropylmethylcellulose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate80, pregelatinized starch, sodium starch glycolate and titanium dioxide. Graphic formula. Chemical name. 7-Chloro-4-4-diethylamino-1-methylbutylaminoquinoline phosphate. Chloroquine phosphate may exist in 2 polymorphic forms differing in melting temperature, one of which melts at about 194°C, the other at about 215°C; mixtures of the 2 forms melt between 194°C and 215°C. Chloroquine phosphate tablets, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble inwater. Chloroquine phosphate tablets are an antimalarial and amebicidal drug. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine phosphate chemical formula Chloroquine Sigma-Aldrich, Monographs Pharmaceutical substances Chloroquine. Itching from plaquenilPlaquenil sjogren disease doesnt workPlaquenil and muscle weaknessChloroquine phosphate suspension ip in hindi Chloroquine is related in structure to quinine but more potent against Plasmodium falciparum, ovale, malariae and vivax, and better tolerated than quinine. Chloroquine remains the first choice of antimalarial prophylaxis as well as treatment. Chloroquine is available in tablets of 250 and 500 mg in generic forms and under the brand name Aralen. Chloroquine - LiverTox - NCBI Bookshelf. DailyMed - CHLOROQUINE PHOSPHATE tablet. Chloroquine - Wikipedia. Empirical Formula Hill Notation C 18 H 26 ClN 3 2H 3 PO 4. Molecular Weight 515.86. CAS Number 50-63-5 Chloroquine is a chemotherapeutic agent for the clinical treatment of malaria. Chloroquine is able to bind to DNA, and inhibit DNA replication and RNA synthesis which in turn results in cell death. The effect of Chloroquine may also be related to the formation of a toxic heme-Chloroquine complex. The chemical name of chloroquine phosphate in chemical abstracts is found under the heading Quinoline and designated as 7-Chloro- 4-4-diethylamino-1-methylbutylamino quinoline diphosphate. Chloroquine phosphate is a white, odorless, crystalline powder having a bitter taste it discolors gradually on exposure to light.