I developed congestive heart failure and was taken off all RA meds except prednisone for a year. For years, I have been complaining to any of my doctors, who would listen, about the dizziness. I went back to my rheumatologist and he prescribed plaquenil again. In the beginning ( The first year or two) It really helped, with my symptoms, with lupus. This past two years, the dizziness has now, turned in to vertigo. Allegra d and plaquenil Plaquenil oct guidelines Renal clearance in rheumatoid arthritis RA patients taking PLAQUENIL for at least six months seemed to be similar to that of the single dose studies in volunteers, suggesting that no change occurs with chronic dosing. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil is NOT known to start working that fast. It takes anywhere from 4-6 months before the affects of Plaquenil are seen/felt. This is the case with everyone I know that takes it. My rheumy has saidand everything I've read on Plaquenil that Plaquenil NEEDS that amount of time to build in your system before it stats to have beneficial effects. Now, that I have read this site, explanation of plaquenil, I think the mystery is solved. After taking it for 6 weeks, I had shortness of breath so I stopped taking it. Again, I have been trying to find out , what have been causing the vertigo. Plaquenil 6 months Hydroxychloroquine Side Effects, Dosage, Uses, and More, Long-Term Side Effects of Plaquenil for Rheumatoid. New guidelines for plaquenil macuopathy 2018 pubmedHow does chloroquine work against malariaPlaquenil ibdIs plaquenil used to treat osteoarthritisPlaquenil vs generic hydroxychloroquine Plaquenil is a slow-acting drug. People who take Plaquenil may begin to notice improvement after one or two months. It may take up to six months before the full benefits of Plaquenil are realized. Taking Plaquenil for Rheumatoid Arthritis. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil Uses, Dosage & Side Effects -. After a month my severe muscle pains went down from an average of 15 incidents per month, to 6 per month, and after a few more months, to just 2-3 per month. I had never gone through even one month of such drastically reduced muscle pain in the 4 years since it started. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Usually Plaquenil related hair loss starts 2-6 months after the Plaquenil was started. We call this a drug induced telogen effluvium. If the Plaquenil was started 10 years ago and a patient reports hair loss last month, it’s not very likely that the Plaquenil is the culprit.