On the skin, lichen planus usually appears as purplish, itchy, flat bumps that develop over several weeks. In the mouth, vagina and other areas covered by a mucous membrane, lichen planus forms lacy white patches, sometimes with painful sores. Scleroderma plaquenil Psoriasis and hydroxychloroquine The cause of lichen planus is unknown but it is thought to be an autoimmune disorder in which white blood cells attack and destroy skin cells expressing unknown antigens. Triggering factors may include pharmacologic agents, contact sensitizers or infectious agents. 5 Lichen Planopilaris is the specific name given to lichen planus on the scalp that causes permanent scarring alopecia with inflammation around affected hair follicles. It mostly affects middle-aged adults as distinct patches of hair loss. A variety of systemic agents are used to treat lichen planopilaris LPP with a limited evidence base. The aim of our study was to retrospectively review the response rate to and tolerability of hydroxychloroquine in a cohort of patients with LPP in an effort to add to the evidence base for its use. If the condition causes pain or significant itching, you may need prescription drugs. See your doctor if tiny bumps or a rash-like condition appears on your skin for no apparent reason, such as a known allergic reaction or contact with poison ivy. Most people can manage typical, mild cases of lichen planus at home, without medical care. Lichen planus hydroxychloroquine Lichen planus - Symptoms and causes - Mayo Clinic, Lichen Planus - American Osteopathic College of Dermatology. Plaquenil oct of maculaWhat eye exams do you need for plaquenilChloroquine side effects pregnancyArtemisia annua taken with hydroxychloroquineChloroquine base dose Clobetasol oral rinse is a topical steroid commonly used to treat oral lichen planus. Hydroxychloroquine, a drug that was originally used to treat malaria and is now also approved for lupus and rheumatoid arthritis, has been tried for lichen planus in small-scale studies with some evidence of benefit. Hydroxychloroquine vs. Clobetasol Rinse to Treat Oral.. The role of hydroxychloroquine in the treatment of lichen.. Lichenoid drug eruption DermNet NZ. Jun 15, 2017 The cause of lichen planus is unknown but it is thought to be an autoimmune disorder in which white blood cells attack and destroy skin cells expressing unknown antigens. Triggering factors may include pharmacologic agents, contact sensitizers or infectious agents. 5 Hydroxychloroquine sulphate may be considered among systemic drugs effective in the treatment of the erosive lichen planus of the oral cavity. AB - The erosive lichen planus of the oral cavity is a chronic and difficult to treat disease. Plaquenil hydroxychloroquine "I have dermatomyositis. Plaquenil along with quinicrine treated my hand lesions which were very painful. This took about a year to accomplish. It's been about a year and a half now and I'm starting to react to one or both of the medications. I have a rash all over my body and ulcers and lichen planus in my mouth.