Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Chloroquine concentration transfection Plaquenil 200mg tablets hydroxychloroquine sulphate HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus erythematosus. It is also used to treat malaria. The lowest GoodRx price for the most common version of generic Plaquenil is around $18.60, 90% off the average retail price of $196.17. Serious side effects have been reported with Plaquenil including the following Heart failure. Plaquenil can cause weakening of the heart muscle, resulting in heart your healthcare provider right away if you have some or all of the following symptoms of heart failure. breathlessness; swelling of the legs; irregular heart beat; fatigue; dizziness If common side effects do occur, they are usually minor and last only for a short period of time. Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in three categories common, less common, and rare. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Risks of plaquenil Hydroxychloroquine Side Effects, Dosage, Uses, and More, Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy. Hydroxychloroquine surfactant protein c deficiencyHydroxychloroquine and reduction of metastasis Some people who take Plaquenil have a higher risk of retinal damage than others. They include people taking Plaquenil for 5 or more years. people taking Plaquenil at higher doses than recommended. people who already have retinal disease. people who already have kidney or liver disease. people over 60 years old. Who Is at Risk for Vision Loss with Plaquenil? - American.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Rx Side Effects New Plaquenil Guidelines and More - American.. For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Aug 14, 2017 Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Plaquenil should be administered with caution in patients having glucose-6-phosphate dehydrogenase G-6-PD deficiency. Dermatologic Effects Dermatologic reactions to Plaquenil may occur and, therefore, proper care should be exercised when it is administered to any patient receiving a drug with a significant tendency to produce dermatitis.