Plaquenil dose based on weight

Discussion in 'Hydroxychloroquine Sulfate' started by Sega, 10-Mar-2020.

  1. referso Guest

    Plaquenil dose based on weight


    If a patient is overweight, one should use the ideal body weight to assess whether the doaily dose is in the toxic range (/= 6.5 mg/kg/day). This graph shows various formulas that have been proposed for deriving ideal body weight for women, because virtually all cases of hydroxychloroquine toxicity have been female.

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    Summary Weight increased is found among people who take Plaquenil, especially for people who are female, 60+ old, have been taking the drug for 1 month, also take medication Actemra, and have Pain. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration. Nov 25, 2019 Alternate dosing based on body weight A total dose representing 25 mg/kg is administered in 3 days, as follows First dose 10 mg base/kg not to exceed 620 mg base orally Second dose 5 mg base/kg not to exceed 310 mg base orally 6 hours after first dose Third dose 5 mg base/kg orally 18 hours after second dose By the old standards, obese people, if dosed by their actual weight, could be overmedicated, Dr. Marmor said. If you’re short, the standard prescription of 200 mg of Plaquenil, twice daily, is too much, he said. The recommended dosage is no more than 6.5 mg/kg/day, using the standard known as “ideal weight,” which factors in height. Dr.

    For this dosage, any woman with an ideal body weight less than 135 pounds would be in the toxic dose range. The usual hydroxychloroquine dose that is prescribed is 400 mg/day.

    Plaquenil dose based on weight

    Hydroxychloroquine Plaquenil Toxicity and Recommendations for Screening, Hydroxychloroquine Dosage Guide with Precautions -

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  4. Adults. 200 mg 155 mg base to 400 mg 310 mg base PO per day, administered as a single dose or in 2 divided doses. Antimalarials and/or glucocorticoids are of benefit and may be used for the treatment of SLE without major organ manifestations; however, judicious use of hydroxychloroquine is recommended.

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    Any concerns regarding dosage should be discussed with the prescribing physician. Discussion. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a ppatient’s real body weight. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity 1. According to these new guidelines, the risk of HCQ retinal toxicity is less than 1 % in the first year of therapy and less than 2 % up to 10 years of therapy. All patients in the cohort were prescribed hydroxychloroquine not to exceed a dose of 6.5 mg per kilogram. The maximum daily dose prescribed is 400 mg. In those who are on hemodialysis 200 mg was prescribed after each dialysis session. In those with renal insufficiency, the dose was 200mg daily.

     
  5. Edwin Well-Known Member

    Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine - Wikipedia Plaquenil hydroxychloroquine sulfate dose, indications. How is plaquenil hydroxychloroquine used to treat lupus?
     
  6. ddddd User

    Plaquenil Monograph for Professionals - To date, no widespread evidence of chloroquine resistance in P. malariae, P. ovale, or P. knowlesi. 143 161. Chloroquine-resistant P. falciparum also are resistant to hydroxychloroquine 109 and may be cross-resistant to pyrimethamine or quinine. a Cross-resistance between chloroquine and mefloquine reported in P. falciparum and P. vivax in.

    Chloroquine Resistant Malaria –
     
  7. ZZe Guest

    Chloroquine MedlinePlus Drug Information Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition.

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