There’s no cure for arthritis, which is unfortunate, but feeling better is definitely possible. The progression of RA may be diminished in severity and duration by the combination of medicines and therapy that work best as determined by you and your physician. Chloroquine hemazoin Can hydroxychloroquine cause diarrhea Liver enzymes plaquenil I took Plaquenil 200x2 from 2012-2016, along with Prednisone to start. Due to the fact, I could not use my hands because of the swelling, I risked the possible vision problems. By 2012, symptom free and still fearful of vision loss, I stopped the drug. The exact hydroxychloroquine mechanism of action is unclear, although it does work to interrupt the communication of immune system cells to decrease swelling, pain, and joint damage. 1, 2, 3, 5 From the community “My Rheumatologist recently put me on Hydroxychoroquine for treating osteoarthritis and joint cysts in my hands and every other. Plaquenil for fatigue and pain. My dr said the Plaquenil takes long time to start working, but for some people, like me, it has a great long term benefit. Being able to stop joint damage can lessen pain and mean a better quality of life. You can also put off joint damage, and in some cases, you can do more than just slow it down. When does plaquenil start working How long did Plaquenil/Hydroxychloroquine take., Hydroxychloroquine Plaquenil Success, Reviews and Side Effects Hydroxychloroquine plaquenil for malaria protectionFibro and plaquenilChloroquine is used for whatLdn and plaquenil Plaquenil hydroxychloroquine "Hi, I was taking the generic form of plaquenil for over 10 years for rheumatoid arthritis. It took a few weeks to see it work but what a change for the better. It took a few weeks to see it work but what a change for the better. Hydroxychloroquine User Reviews for Rheumatoid Arthritis at.. Plaquenil for fatigue and pain DailyStrength. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Symptoms can start to improve in one to two months, but it may take up to six months before the full benefits of this medication are experienced. Side Effects Hydroxychloroquine typically is very well tolerated. Mar 24, 2011 What next if plaquenil doesn't work. for me methotreaxte and plaquenil does't work and i' intonate of sulfa so i am started embrel which states you have to have. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Most people who take Plaquenil also take other medicines for pain and stiffness. How does Plaquenil work? Plaquenil changes the way your immune system works.