The condition often accompanies other immune system disorders, such as rheumatoid arthritis and lupus. In Sjogren's syndrome, the mucous membranes and moisture-secreting glands of your eyes and mouth are usually affected first — resulting in decreased tears and saliva. Your immune system mistakenly attacks your body's own cells and tissues. Does prednisone and plaquenil work for ankylosing spondylitis Best prescription savings card hydroxychloroquine 200mg Plaquenil schedule Abstract. OBJECTIVE To evaluate the effect of hydroxychloroquine treatment on interleukin 6 IL6, hyaluronic acid HA, and soluble interleukin 2 receptor sIL2R concentrations in the saliva and serum of patients with primary Sjögren’s syndrome SS. METHODS Fourteen SS patients treated with hydroxychloroquine 200 mg/day for 12 months were investigated in an open prospective study. Sjögren’s syndrome is an autoimmune disease. About half the time, it occurs along with other autoimmune conditions, like rheumatoid arthritis or lupus. Sjögren’s syndrome may cause arthritis, or joint pain, and chronic dry mouth or eyes. Inflammation of the tear ducts and saliva glands cause dryness and irritation. Hydroxychloroquine treatment downregulates systemic interferon activation in primary Sjögren’s syndrome in the JOQUER randomized trial Iris L A Bodewes. Department of Immunology, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands. Certain genes put people at higher risk of the disorder, but it appears that a triggering mechanism — such as infection with a particular virus or strain of bacteria — is also necessary. Scientists aren't certain why some people develop Sjogren's syndrome. Sjögren's syndrome hydroxychloroquine Sjögrens Syndrome - Arthritis Foundation, PATIENT FACT SHEET Sjögren’s Syndrome Is hydroxychloroquine sulfate an immunosuppressive drug A medication called hydroxychloroquine is sometimes recommended by Sjögren's syndrome specialists as a treatment for joint pain or stiffness if other methods haven't helped. But it isn't suitable for everyone and can take several months to work. It can also cause side effects such as tummy pain and feeling sick. Sjögren's syndrome - Treatment - NHS. Hydroxychloroquine treatment downregulates systemic.. Sjogren's syndrome - Symptoms and causes - Mayo Clinic. User Reviews for Plaquenil to treat Sjogren's Syndrome. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Hydroxychloroquine Plaquenil is commonly used for treating joint pain in Sjögren’s syndrome patients, based in part on its efficacy in treating the joint pain of patients with systemic lupus erythematosus and rheumatoid arthritis. Common complaints consist of mouth sores, stomach upset, loss of appetite, fatigue or headache. Some patients notice mild hair loss, more of a thinning, usually more noticeable to the patient than to friends or family. Some patients develop a cough or low grade fever. Rarely, a pneumonia-like syndrome can complicate treatment.