Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Eosinophilotaxis hydroxychloroquine Chloroquine merozites Plaquenil treatment with macular degeneration What to expect when taking plaquenil for the first time Total dose 2.5 g of chloroquine phosphate 1.5 g base in 3 days. If your body weight is less than 60 kg, use oral medication at a dose of Initial dose 16.7 mg Chloroquine phosphate / kg 10 mg base / kg Second dose 6 hours after initial dose 8.3 mg chloroquine phosphate / kg 5 mg base / kg Chloroquine Interactions. Antacids, such as Tagamet cimetidine and others. Arsenic trioxide. Rheumatrex, Trexall methotrexate Tylenol acetaminophen Iron products. Kaolin. Niacin. Rifadin or Rimactane rifampin Nydrazid isoniazid Medication for irregular heartbeat. Chloroquine is only effective against malaria from certain areas of the world. chloroquine may worsen psoriasis, seizures, hearing problems, and liver conditions. ADVERTISEMENT Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Advantages of chloroquine Effectiveness of Chloroquine and Hydroxychloroquine in., Chloroquine Aralen - Side Effects, Dosage, Interactions. Mefloquine vs chloroquineHydroxychloroquine blood monitoringPlaquenil 200 mg oral tabletPlaquenil drug category Chloroquine phosphate is used occasionally to decrease the symptoms of rheumatoid arthritis and to treat systemic and discoid lupus erythematosus, scleroderma, pemphigus, lichen planus, polymyositis, sarcoidosis, and porphyria cutanea tarda. Talk to your doctor about the possible risks of using this drug for your condition. Chloroquine MedlinePlus Drug Information. Compare Plaquenil vs Chloroquine -. Chloroquine Side Effects Common, Severe, Long Term.. Chloroquine is administered orally as chloroquine phosphate. It also can be given by intramuscular injection as chloroquine hydrochloride. Chloroquine is effective against susceptible strains of the malarial parasites Plasmodium vivax, P. ovale, and P. falciparum, as well as certain parasitic worms and amoebas. Use chloroquine with caution in patients with cardiac disease or other conditions that may increase the risk of QT prolongation including cardiac arrhythmias, congenital long QT syndrome, heart failure, bradycardia less than 50 bpm, myocardial infarction, hypertension. New insights into the antiviral effects of Chloroquine. described the potentially therapeutic benefits of the quinoline antimalarial chloroquine in viral diseases such as HIV-1/AIDS and severe.