It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine mechanism of action in sle How does plaquenil cause blindness Hydroxychloroquine tablets Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Incidence not known. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or. Common Plaquenil side effects - a study from FDA data Summary In this review, we analyze Plaquenil side effects by the time on the drug, gender and age of the people who have side effects while taking Plaquenil. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine adverse effects Hydroxychloroquine Indications, Side Effects, Warnings -, Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Quinacrine with hydroxychloroquine lupus profundus Consumer information about the medication HYDROXYCHLOROQUINE - ORAL Plaquenil, includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug HYDROXYCHLOROQUINE - ORAL. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Common Plaquenil side effects a study from FDA data.. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects.. Get medical help right away if you have any very serious side effects, including sensitivity to light, vision changes e.g. blurred vision, seeing light flashes/streaks/halos, missing/blacked-out areas of vision, muscle weakness, numbness/tingling/pain of the arms/legs. Hydroxychloroquine is a disease-modifying anti-rheumatic drug DMARD used for rheumatoid arthritis and lupus. Learn how long it takes, risks and side-effects. The risk of retinal toxicity is dependent on several factors A daily dose of hydroxychloroquine 5.0 mg/kg using the patient's body weight. Severe renal impairment. Concomitant use of tamoxifen. Duration of use 5 years.