Just google does low dose naltrexone cause a herxheimer's reaction and I am sure you will find a lot of info. Did you have your med compounded from pure naltrexone powder or from ground up 50 mg Revia/generic equivalent? Here is how it applies to AP https://en.wikipedia.org/wiki/Type_III_hypersensitivity https://chronicillnessrecovery.org/index.php? Hi, Boise CGM- Can you please describe the "awful"? Happy to help if you can provide a few key details. Hydroxychloroquine neuropathy Plaquenil therapy and eyes Lexapro - can it start making you feel worse before making you feel better? Asked by Btaylor2012 Updated 11 August 2019 Topics lexapro, depression, anxiety, generic, antidepressant User Reviews for Hydroxychloroquine to treat Undifferentiated Connective Tissue Disease. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare. Plaquenil hydroxychloroquine "When first diagnosed with rheumatoid arthritis RA plaquinel worked after a couple weeks. I was in remission soI stopped but Dr upset as he said it was important to keep damage to joints down. Anyway the RA flared and I'm back taking one a day. Hoping to feel better again but seems slow. He's excellent, open-minded, and in my opinion quite brilliant - and had the following comment when I asked him about LDN in an email. Kk I've quoted my scleroderma specialist on LDN here before, but will copy and paste it again. Will i feel worse before i feel better on plaquenil PLAQUENIL Side Effects, Reviews by Patients -, User Reviews for Hydroxychloroquine to treat. - Calcium chloroquine fc review I recently decided to stop taking Plaquenil because I was having constant chest pains even more so than I usually have due to Lupus. Since I have not taken it my chest feels so much better which is odd because chest pain is not listed as a side effect. Also I noticed that the Plaquenil I think was making me feel different but not in a good way. Had to stop taking Plaquenil -. Hydroxychloroquine User Reviews for Rheumatoid Arthritis.. Plaquenil Drug and Medication User Reviews on RxList. Plaquenil hydroxychloroquine for Systemic Lupus Erythematosus "I've been taking Plaquenil for 6 days now and I already notice a difference in my SLE. I almost feel normal. Before I struggled with fatigue and pain. Since its a mild stimulant it helps with my energy and my body is feeling so much better. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. After about 3 or so weeks i started to feel better and seemed to overcome all my side effects. I wouldn't say that plaquenil has kicked in yet only been 6 weeks but pred is definitely helping. I have tried to wean pred below 10mg and can't, so hopefully plaquenil will work in order for me to attempt weaning pred.